[Detection of p53 gene mutation in paraffin-embedded asbestos-related lung cancer tissue].

Article

[Detection of p53 gene mutation in paraffin-embedded asbestos-related lung cancer tissue].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Jul 1997

Fu D, Liu B, Wang H

Abstract excerpt

Paraffin-embedded asbestos-related lung cancer tissue of ten cases was analyzed with polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) to study its genetic mutation of exon 5, 7 and 8 of anti-oncogene p53 by silver stain. Results showed that fragment of exon 7 or 8 of p...

Topics

Adenocarcinoma
Asbestosis
Genes, p53
Humans
Lung Neoplasms
Mutation
Paraffin Embedding
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

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