Article
[Detection of p53 gene mutation in paraffin-embedded asbestos-related lung cancer tissue].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Jul 1997
Fu D, Liu B, Wang H
Abstract excerpt
Paraffin-embedded asbestos-related lung cancer tissue of ten cases was analyzed with polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) to study its genetic mutation of exon 5, 7 and 8 of anti-oncogene p53 by silver stain. Results showed that fragment of exon 7 or 8 of p53 gene in four cases was positive in silver-staining analysis of PCR-SSCP. Exon 7 or 8 fragments of p53 gene was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
