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Article

[High resolution melting analysis for detecting p53 gene mutations in patients with non-small cell lung cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Oct 2011

Chen Zhihong, An Shejuan, Xie Zhi, Yan Honghong, Chen Jianguang, Su Jian, Zhang Xuchao, Niu Feiyu, Guo Weibang, Wu Yilong

Abstract excerpt

BACKGROUND AND OBJECTIVE: It has been proven that p53 gene was related to many human cancers. The mutations in p53 gene play an important role in carcinogensis and mostly happened in exon 5-8. The aim of this study is to establish a high resolution melting (HRM) assay to detect p53 mutations from patients with non-small cell lung cancer (NSCLC), to investigate the characteristics of p53 gene mutations, and to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22008105
DOI: 10.3779/j.issn.1009-3419.2011.10.01
PMCID: PMC5999946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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