Article
[A preliminary study on p53 gene in lung cancer tissues of workers exposed to silica and welding fumes].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 May 1997
Liu B, Zhou P, Miao Q
Abstract excerpt
Mutations of suppressor gene p53 was studied in 36 cases of silica related lung cancer and 6 cases of welding fume related lung cancer with immunohistochemical and PCR-SSCP methods. Cancer tissues were embedded in paraffin and stored for 13.4 years in average. Results revealed that there was abnormal mobility shift of electrophoresis in 18 cases with 20 point mutations of 42 specimens tested, accounted for 42.9%,...
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