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Article

Low density DNA microarray for detection of most frequent TP53 missense point mutations.

BMC biotechnology - 15 Feb 2005

Rangel-López Angélica, Maldonado-Rodríguez Rogelio, Salcedo-Vargas Mauricio, Espinosa-Lara Juana Mercedes, Méndez-Tenorio Alfonso, Beattie Kenneth L

Abstract excerpt

BACKGROUND: We have developed an oligonucleotide microarray (genosensor) utilizing a double tandem hybridization technique to search for 9 point mutations located in the most frequently altered codons of the TP53 gene. Isolated and multiplexed PCR products, 108 and 92 bp long, from exons 7 and 8, respectively, were obtained from 24 different samples. Single-stranded target DNA was then prepared from isolated or...

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Identifiers

PMID: 15713227
DOI: 10.1186/1472-6750-5-8
PMCID: PMC553977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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