Article
A mdg4 retrotransposon screen for X-linked female sterile alleles and its relationship with the transcription factor OVO.
G3 (Bethesda, Md.) - 3 Jun 2026
Benner Leif, Oliver Brian
Abstract excerpt
In the germline, the mdg4 retrotransposon integrates in close proximity to the location of OVO DNA binding motifs, suggesting that insertion bias is driven by the OVO transcription factor. A classical genetic example of this is the reversion of the dominant female-sterile allele, ovoD1, by the transposition of mdg4 into the ovo promoter where OVO protein binds. We wanted to take advantage of this relationship and...
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