Article
The transitional ER defines a boundary for quality control in the secretion of tsO45 VSV glycoprotein.
Traffic (Copenhagen, Denmark) - 1 Nov 2002
Mezzacasa Anna, Helenius Ari
Abstract excerpt
Quality control in the secretory pathway limits forward transport of newly synthesized cargo proteins to those that have acquired their fully folded conformation. To determine which organelles participate in this conformation-dependent sorting process, we analyzed the trafficking of the temperature-sensitive, thermo-reversible folding mutant of vesicular stomatitis virus glycoprotein (tsO45 G protein) in VERO...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
