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Article

Minor folding defects trigger local modification of glycoproteins by the ER folding sensor GT.

The EMBO journal - 4 May 2005

Ritter Christiane, Quirin Katharina, Kowarik Michael, Helenius Ari

Abstract excerpt

UDP-glucose:glycoprotein glucosyltransferase (GT) is a key component of the glycoprotein-specific folding and quality control system in the endoplasmic reticulum. By exclusively reglucosylating incompletely folded and assembled glycoproteins, it serves as a folding sensor that prolongs the association of newly synthesized glycoproteins with the chaperone-like lectins calnexin and calreticulin. Here, we address...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15861139
DOI: 10.1038/sj.emboj.7600645
PMCID: PMC1142578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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