Article
The length of cargo-protein transmembrane segments drives secretory transport by facilitating cargo concentration in export domains.
Journal of cell science - 1 Jun 2009
Dukhovny Anna, Yaffe Yakey, Shepshelovitch Jeanne, Hirschberg Koret
Abstract excerpt
The cellular destination of secretory proteins is determined by interactions of their targeting motifs with coat-protein complexes. The transmembrane domain (TMD) of secretory proteins also plays a central role in their transport and targeting. However, a comprehensive model that considers both T...
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