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Article

Inefficient quality control of thermosensitive proteins on the plasma membrane.

PloS one - 1 Jan 2009

Lewis Michael J, Pelham Hugh R B

Abstract excerpt

BACKGROUND: Misfolded proteins are generally recognised by cellular quality control machinery, which typically results in their ubiquitination and degradation. For soluble cytoplasmic proteins, degradation is mediated by the proteasome. Membrane proteins that fail to fold correctly are subject to...

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Identifiers

PMID: 19337370
DOI: 10.1371/journal.pone.0005038
PMCID: PMC2659772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19337370-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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