Article
Three distinct steps in transport of vesicular stomatitis virus glycoprotein from the ER to the cell surface in vivo with differential sensitivities to GTP gamma S.
Journal of cell science - 1 Jul 1998
Pepperkok R, Lowe M, Burke B, Kreis T E
Abstract excerpt
Microinjected GTP gamma S revealed three distinct steps in the exocytic transport of the temperature sensitive glycoprotein of vesicular stomatitis virus (ts-O45-G) from the ER to the cell surface in intact Vero cells. While COPII dependent export of ts-O45-G from the ER is blocked in cells injected with recombinant protein of a dominant mutant of SAR1a (SAR1a[H79G]) inhibited in GTP hydrolysis, neither injected...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
