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Article

TNF-alpha promoter region gene polymorphisms in HIV-positive patients with lipodystrophy.

AIDS (London, England) - 18 Oct 2002

Maher Bridget, Alfirevic Ana, Vilar F Javier, Wilkins Edmund G L, Park B Kevin, Pirmohamed Munir

Abstract excerpt

OBJECTIVE: The pathogenic mechanisms underlying lipodystrophy in HIV-positive patients are largely unknown. TNF-alpha has many actions that are consistent with the features of lipodystrophy; therefore, an analysis was carried out to determine whether functionally active polymorphisms in the promoter region of the TNF-alpha gene are associated with the development of lipodystrophy. DESIGN: Genetic case-control...

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Share to Antiretroviral Therapy, Highly Active
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 12370499
DOI: 10.1097/00002030-200210180-00005

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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