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Article

The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome.

AIDS (London, England) - 23 Oct 2010

Montes Angel H, Valle-Garay Eulalia, Suarez-Zarracina Tomas, Melon Santiago, Martinez Esteban, Carton Jose A, Collazos Julio, Asensi Víctor

Abstract excerpt

OBJECTIVE: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in extracellular matrix remodelling and adipocyte differentiation and are inhibited by antiretrovirals. MMPs and TIMPs and their single nucleotide polymorphisms (SNPs) might contribute to the HAART-related lipodystrophic syndrome pathogenesis. DESIGN AND SETTING: Cross-sectional study in a university-based outpatient...

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Source

Identifiers

PMID: 20852404
DOI: 10.1097/QAD.0b013e32833e922c

Genes

MMP1
TIMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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