Article
The effect of polymorphisms in candidate genes on the long-term risk of lipodystrophy and dyslipidemia in HIV-infected white patients starting antiretroviral therapy.
AIDS research and human retroviruses - 1 Dec 2011
Marzocchetti Angela, Schwarz Jessica, Di Giambenedetto Simona, Colafigli Manuela, Bracciale Laura, Fabbiani Massimilliano, Fantoni Massimo, Trecarichi Enrico, Cauda Roberto, De Luca Andrea
Abstract excerpt
We investigated whether polymorphisms in human candidate genes could be associated with a different risk of developing lipodystrophy and dyslipidemia in HIV-infected patients starting combination antiretroviral therapy (cART). Genomic DNA samples from white HIV-1-infected patients were analyzed for seven polymorphisms located in the MDR1, TNF-α, APM1, APOE, and LPL genes. Lipid data were retrospectively collected...
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