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Article

Adipogenic gene variants in patients with HIV-associated lipodystrophy.

Pharmacogenetics and genomics - 1 Feb 2011

Pushpakom Sudeep P, Owen Andrew, Vilar F Javier, Castro Hannah, Dunn David T, Back David J, Pirmohamed Munir

Abstract excerpt

OBJECTIVES: Although highly active antiretroviral therapy (HAART) has been hugely beneficial in the treatment of HIV, HIV lipodystrophy (HIVLD) associated with HAART is a serious adverse effect, with long-term consequences including metabolic disturbances and an increased risk of atherosclerotic disease. Although HIVLD is clearly related to the drug regimen, individual susceptibility also plays a role. We...

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Source

Identifiers

PMID: 21178827
DOI: 10.1097/FPC.0b013e328342a917

Genes

LPIN1
ZMPSTE24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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