Article
TNF microsatellite alleles may confer protection against the development of lipodystrophy syndrome in Brazilian HIV patients.
International journal of immunogenetics - 1 Oct 2010
Silva M M, Simões R T, Castelli E C, Mendes-Junior C T, Deghaide N H S, Tsuda L C, Machado A A, Donadi E A, Fernandes A P M
Abstract excerpt
The aim of this study was to evaluate the frequency of TNFa-e microsatellites and the promoter region (TNF-308 and TNF-238) in HIV/AIDS-infected patients presenting or not lipodystrophy syndrome (LS). The design is the genetic case-control association study. Microsatellite and the TNF promoter region polymorphisms were amplified by PCR and submitted to polyacrylamide gel electrophoresis. The genotypes and allele...
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