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Article

Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha.

Acta pharmacologica Sinica - 1 Oct 2002

Yan Feng-Xiang, Yamamoto Shuichi, Zhou Hui-Ping, Tai Hsin-Hsiung, Liao Duan-Fang

Abstract excerpt

AIM: To identify the specific serine/threonine residues in the C-terminal tail of thromboxane receptor alpha (TPalpha) being phosphorylated and desensitized, and various alanine mutants of these serine/threonine residues were checked for their ability to serve as substrates. METHODS: To facilitate the identification of the intracellular domains involved in phosphorylation, glutathione S-transferase...

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PMID: 12370102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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