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Article

LPA3 Receptor Phosphorylation Sites: Roles in Signaling and Internalization.

International journal of molecular sciences - 18 May 2024

Solís K Helivier, Romero-Ávila M Teresa, Rincón-Heredia Ruth, García-Sáinz J Adolfo

Abstract excerpt

Lysophosphatidic acid (LPA) type 3 (LPA3) receptor mutants were generated in which the sites detected phosphorylated were substituted by non-phosphorylatable amino acids. Substitutions were made in the intracellular loop 3 (IL3 mutant), the carboxyl terminus (Ctail), and both domains (IL3/Ctail). The wild-type (WT) receptor and the mutants were expressed in T-REx HEK293 cells, and the consequences of the...

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Identifiers

PMID: 38791546
DOI: 10.3390/ijms25105508
PMCID: PMC11122405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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