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Article

Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 2002

Fornage Myriam, Hinojos Cruz A, Nurowska Barbara W, Boerwinkle Eric, Hammock Bruce D, Morisseau Christophe H P, Doris Peter A

Abstract excerpt

We measured soluble epoxide hydrolase (sEH) renal gene expression in prehypertensive (4 to 5 weeks old) spontaneously hypertensive rats of the Heidelberg SP substrain (SHR [Heid]) and when blood pressure levels entered the hypertensive plateau (17 to 18 weeks old) and compared expression with matched Wistar-Kyoto (WKY [Heid]) rats. Less expression of the gene encoding sEH (EPHX2) was observed in SHR (Heid) than...

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Source

Identifiers

PMID: 12364351
DOI: 10.1161/01.hyp.0000032278.75806.68

Genes

EPHX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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