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Article

In vivo activity of epoxide hydrolase according to sequence variation affects the progression of human IgA nephropathy.

American journal of physiology. Renal physiology - 1 Jun 2011

Lee Jung Pyo, Yang Seung Hee, Kim Dong Ki, Lee Hajeong, Kim Bora, Cho Joo-Youn, Yu Kyung-Sang, Paik Jin Ho, Kim Myounghee, Lim Chun Soo, Kim Yon Su

Abstract excerpt

Epoxyeicosatrienoic acid (EET) regulates the functional integrity of the endothelium. It is hypothesized that the activity of epoxide hydrolase (EPHX2), which determines EET concentration through hydrolysis, may affect the progression of glomerulonephritis. Here, we evaluated the relationship between genetic variations, the in vivo activity of EPHX2, and progression of IgA nephropathy (IgAN). Three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21429967
DOI: 10.1152/ajprenal.00733.2010

Genes

EPHX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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In vivo activity of epoxide hydrolase according to sequence variation affects the progression of human IgA nephropathy.PMID 21429967Read ↗

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