Article
Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
Environmental and molecular mutagenesis - 1 Jan 2002
Liu Chin-San, Chen Haw-Wen, Lii Chong-Kuei, Tsai Ching-Shan, Kuo Chen-Ling, Wei Yau-Huei
Abstract excerpt
The effects of long-term smoking on mitochondrial DNA (mtDNA) deletions in hair follicles were investigated in subjects with different antioxidant capacity. Twenty-two male smokers with a smoking index of greater than 5 pack-years and without any known systemic diseases were recruited for this study. Forty healthy nonsmoking males were included as controls. We found that the concentrations of ascorbate and...
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