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Article

Thyroid/parathyroid function and fluoride: role of mitochondrial DNA and SOD genetic variations.

Journal of endocrinological investigation - 1 Jun 2026

Sun Qing, Feng Zichen, Sun Long, Li Chunxiang, Wang Guoqing, Niu Shu, Wang Yan, Wan Hedan, Huang Hui, Zhu Jingyuan, Yu Fangfang, Zhou Guoyu, Ba Yue

Abstract excerpt

Emerging evidence indicates excessive fluoride exposure damage thyroid/parathyroid, with oxidative stress and mitochondrial dysfunction as crucial mechanisms. However, epidemiological research on their involvement in fluoride-induced thyroid/parathyroid dysfunction and modification of oxidative stress-related SNPs are insufficient. Therefore, we conducted a cross-sectional study (n = 401) among children aged 7-13...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41678012
DOI: 10.1007/s40618-026-02823-5

Genes

SOD2
SOD3
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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