Article
Tobacco, antioxidant enzymes, oxidative stress, and genetic susceptibility in oral cancer.
American journal of clinical oncology - 1 Oct 2008
Patel Beena P, Rawal Upendra M, Rawal Rakesh M, Shukla Shilin N, Patel Prabhudas S
Abstract excerpt
OBJECTIVES: Oral cancer accounts third of all malignancies in India. Tobacco use, the major etiological factor for oral cancer is known to generate free radicals resulting in alterations in antioxidant enzymes like, glutathione-S-transferase (GST), glutathione reductase, superoxide dismutase, catalase, and glutathione peroxidase as well as lipid peroxidation and total thiol. Therefore, it is of fundamental...
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