Markers for cytogenetic damage in smokers: associations with plasma antioxidants and glutathione S-transferase mu.

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Article

Markers for cytogenetic damage in smokers: associations with plasma antioxidants and glutathione S-transferase mu.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000

van Poppel G, Verhagen H, van 't Veer P, van Bladeren P J

Abstract excerpt

Biomarkers for increased cytogenetic damage in smokers include sister chromatid exchanges (SCE) in peripheral lymphocytes and micronuclei in sputum cells. These markers may reflect increased cancer risk. Increased cancer risk has also been associated with lower blood levels of the antioxidants beta-carotene and vitamin C and with genetic deficiency of the detoxification enzyme glutathione S-transferase mu...

Topics

Adult
Alcohol Drinking
Antioxidants
Ascorbic Acid
Biomarkers
Carotenoids
Cotinine
Cross-Sectional Studies
Cytogenetics
Dehydroascorbic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glutathione Transferase

Humans

Lymphocytes

Male

Micronuclei, Chromosome-Defective

Phenotype

Sister Chromatid Exchange

Smoking

Source

Open in PubMed

Identifiers

PMID: 8220088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8220088-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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