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Oxidative Stress-related Alteration of the Copy Number of Mitochondrial DNA in Human Leukocytes

1 Dec 2003

Abstract excerpt

The role of oxidative stress in the regulation of the copy number of mitochondrial DNA (mtDNA) in human leukocytes is unclear. In this study, we investigated the redox factors in plasma that may contribute to the alteration of mtDNA copy number in human leukocytes. A total of 156 healthy subjects of 25-80 years of age who exhibited no significant difference in the distribution of subpopulations of leukocytes in...

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PMID: 14753755
DOI: 10.1080/10715760310001621342

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