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Article

CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity.

Clinical pharmacology and therapeutics - 1 Mar 2002

García-Martín Elena, Martínez Carmen, Pizarro Rosa M, García-Gamito Francisco J, Gullsten Harriet, Raunio Hannu, Agúndez José A G

Abstract excerpt

OBJECTIVE: Our objective was to evaluate the presence of CYP3A4 gene variants in white individuals with low CYP3A4 enzyme activity. METHODS: Persons with extremely low enzyme activity, either in vitro or in vivo, were selected in a panel of 97 healthy subjects. Genetic analyses for CYP3A4 variant...

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Identifiers

PMID: 11907494
DOI: 10.1067/mcp.2002.121371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11907494-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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