Article
Analysis of CYP3A4*1B and CYP3A5*3 polymorphisms in population of Bosnia and Herzegovina.
Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina - 1 Feb 2011
Semiz Sabina, Dujić Tanja, Ostanek Barbara, Prnjavorac Besim, Bego Tamer, Malenica Maja, Mlinar Barbara, Marc Janja, Causević Adlija
Abstract excerpt
AIM: Differences in the frequency of distribution of the cytochrome P450 (CYP) allelic variants have been demonstrated between distinct ethnic groups, contributing to observed interindividual variation in drug response. In this study we determined, for the first time, prevalence of the common allelic variants of the polymorphic CYP enzymes, CYP3A4*1B and CYP3A5*3, in the population of Bosnia and Herzegovina (BH)....
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