Article
DNA polymerase III from Escherichia coli cells expressing mutA mistranslator tRNA is error-prone.
The Journal of biological chemistry - 29 Nov 2002
Al Mamun Abu Amar M, Marians Kenneth J, Humayun M Zafri
Abstract excerpt
Translational stress-induced mutagenesis (TSM) refers to the elevated mutagenesis observed in Escherichia coli cells in which mistranslation has been increased as a result of mutations in tRNA genes (such as mutA) or by exposure to streptomycin. TSM does not require lexA-regulated SOS functions but is suppressed in cells defective for homologous recombination genes. Crude cell-free extracts from TSM-induced E....
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