Article
Genetic polymorphism of cytochrome P4501A1 and susceptibility to oral squamous cell carcinoma and oral precancer lesions associated with smoking/betel use.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Oct 2002
Kao Shou-Yen, Wu Cheng-Hsien, Lin Shu-Chun, Yap Soon-Kiong, Chang Che-Shoa, Wong Yong-Kie, Chi Lin-Yang, Liu Tsung-Yun
Abstract excerpt
BACKGROUND: The importance of the CYP1A1 polymorphisms at exon 7 (Ile/Val) and 3'-untranslated region (3'-UTR) has been controversial in oral squamous cell carcinoma (OSCC) or head and neck SCC (HNSCC) denoting the value of exploring the correlation between these polymorphisms and risk of betel/smoking associated OSCC. It is also important to evaluate the association between CYP1A1 polymorphisms and...
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