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Article

Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer.

Oral oncology - 1 Jul 2002

Hahn Matthias, Hagedorn Gunnar, Kuhlisch Eberhard, Schackert Hans Konrad, Eckelt Uwe

Abstract excerpt

We investigated the association of polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer. Polymerase chain reaction (PCR)-based analyses were performed on genomic DNA of 94 Caucasian patients in Germany and 92 healthy German controls to determine genotypes of polymorphisms in CYP1A1, GSTM1 and NAT2. For CYP1A1, the homozygous mutant genotype Val/Val did not occur. The heterozygous...

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Source

Identifiers

PMID: 12110344
DOI: 10.1016/s1368-8375(01)00086-0

Genes

GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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