Article
The variant of pri-mir-26a-1 polymorphism is associated with decreased risk of betel quid-related oral premalignant lesions and oral squamous cell carcinoma.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Oct 2017
Yang Cheng-Mei, Chen Chien-Chou, Tseng Yu-Kai, Huang Sin-Jhih, Liou Huei-Han, Lee Yi-Cheng, Lee Jang-Hwa, Wang Jyh-Seng, Chen Hung-Chih, Chi Chao-Chuan, Kang Bor-Hwang, Lin Yun-Chung, Tsai Kuo-Wang, Ger Luo-Ping
Abstract excerpt
OBJECTIVES: This case-control study evaluated the association of the single nucleotide polymorphism rs7372209 (T>C) in pri-mir-26a-1 with the risk and progression of betel quid (BQ)-related oral premalignant lesions (OPLs) and oral squamous cell carcinoma (OSCC). STUDY DESIGN: In total, 597 BQ chewers were recruited: 196 healthy controls, 241 patients with OPLs, and 160 patients with OSCC. Genotypes were...
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