Article
Survival in prospectively ascertained familial breast cancer: analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy.
International journal of cancer - 20 Oct 2002
Møller Pål, Borg Ake, Evans D Gareth, Haites Neva, Reis Marta M, Vasen Hans, Anderson Elaine, Steel C Michael, Apold Jaran, Goudie David, Howell Anthony, Lalloo Fiona, Maehle Lovise, Gregory Helen, Heimdal Ketil
Abstract excerpt
Dedicated clinics have been established for the early diagnosis and treatment of women at risk for inherited breast cancer, but the effects of such interventions are currently unproven. This second report on prospectively diagnosed inherited breast cancer from the European collaborating centres supports the previous conclusions and adds information on genetic heterogeneity and the effect of oophorectomy. Of 249...
Topics
- Adult
- Aged
- Breast Neoplasms
- Disease-Free Survival
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Humans
- Middle Aged
