Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.

doi:10.1200/JCO.2005.02.7888

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2006

Pierce Lori J, Levin Albert M, Rebbeck Timothy R, Ben-David Merav A, Friedman Eitan, Solin Lawrence J, Harris Eleanor E, Gaffney David K, Haffty Bruce G, Dawson Laura A, Narod Steven A, Olivotto Ivo A, Eisen Andrea, Whelan Timothy J, Olopade Olufunmilayo I, Isaacs Claudine, Merajver Sofia D, Wong Julia S, Garber Judy E, Weber Barbara L

Abstract excerpt

PURPOSE: We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls. METHODS: A total of 160 BRCA1/2 mutation carriers with breast cancer were matched with 445 controls with sporadic breast cancer. Primary end points were rates of in-breast tumor recurrence (IBTR) and contralateral breast cancers (CBCs). Median...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Canada

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Israel

Share to Multivariate Analysis

Share to Neoplasm Recurrence, Local

Share to Ovariectomy

Share to Radiotherapy, Adjuvant

Source

Open in PubMed

Identifiers

PMID: 16636335
DOI: 10.1200/JCO.2005.02.7888

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.PMID 16636335Read ↗

Surgical management of breast cancer in BRCA-mutation carriers: a systematic review and meta-analysis.Semantic proximity Read ↗

Does breast-conserving surgery with radiotherapy in BRCA-mutation carriers significantly increase ipsilateral breast tumor recurrence? A systematic review and meta-analysis.Semantic proximity Read ↗

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.Semantic proximity Read ↗

Breast Conserving Surgery for BRCA Mutation Carriers-A Systematic Review.Semantic proximity Read ↗

Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers.Semantic proximity Read ↗

Combined breast conservation therapy versus mastectomy for BRCA mutation carriers - A systematic review and meta-analysis.Semantic proximity Read ↗

Impact of BRCA1/2 pathogenic variants on ipsilateral breast tumor recurrence and prognosis following breast-conserving surgery.Semantic proximity Read ↗

Conservative management of breast cancer in BRCA1/2 mutation carriers.Semantic proximity Read ↗

Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status.Semantic proximity Read ↗

Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

Impact of breast surgical procedure on survival in BRCA mutated patients with invasive breast cancer: Mastectomy versus conservative treatment.Semantic proximity Read ↗

Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.