Article
Ten-year survival in patients with BRCA1-negative and BRCA1-positive breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Sept 2013
Huzarski Tomasz, Byrski Tomasz, Gronwald Jacek, Górski Bohdan, Domagala Pawel, Cybulski Cezary, Oszurek Oleg, Szwiec Marek, Gugala Karol, Stawicka Malgorzata, Morawiec Zbigniew, Mierzwa Tomasz, Janiszewska Hanna, Kilar Ewa, Marczyk Elzbieta, Kozak-Klonowska Beata, Siolek Monika, Surdyka Dariusz, Wisniowski Rafal, Posmyk Michal, Sun Ping, Lubinski Jan, Narod Steven A
Abstract excerpt
PURPOSE: To estimate 10-year overall survival (OS) rates for patients with early-onset breast cancer, with and without a BRCA1 mutation, and to identify prognostic factors among those with BRCA1-positive breast cancer. PATIENTS AND METHODS: A total of 3,345 women with stage I to III breast cancer, age ≤ 50 years, were tested for three founder mutations in BRCA1. Information on tumor characteristics and treatments...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
