Article
Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers.
Breast cancer research and treatment - 1 Jul 2014
Tung Nadine, Gaughan Elizabeth, Hacker Michele R, Lee Larissa J, Alexander Brian, Poles Emily, Schnitt Stuart J, Garber Judy E
Abstract excerpt
The majority of breast cancers developing in BRCA1 mutation carriers are triple negative breast cancers (TNBC), an aggressive subtype that accounts for 15-20 % of sporadic breast cancer. We compare the clinical outcome and sites of relapse of TNBC in BRCA1 mutation carriers and non-carriers who received adjuvant chemotherapy. Women with stage I-III TNBC who had BRCA1 testing within 36 months of diagnosis and...
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