Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families.

Breast cancer research and treatment - 1 Jan 2011

Korde Larissa A, Mueller Christine M, Loud Jennifer T, Struewing Jeffery P, Nichols Kathy, Greene Mark H, Mai Phuong L

Abstract excerpt

This analysis addresses risk of breast cancer among women in BRCA-positive families who test negative for the family mutation. We compared the number of prospectively diagnosed breast cancers in 395 mutation-negative women from 28 BRCA1/2-positive families to an age-, race-, and calendar time-specific expected number of breast cancers derived from the SEER 9 Cancer Registry. Study participants contributed a total...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Odds Ratio

Share to Ovariectomy

Share to Risk Assessment

Share to SEER Program

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 20458532
DOI: 10.1007/s10549-010-0923-y
PMCID: PMC3110729

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families.PMID 20458532Read ↗

Prospective study of breast cancer risk for mutation negative women from BRCA1 or BRCA2 mutation positive families.Semantic proximity Read ↗

Population-based estimates of the relation between breast cancer risk, tumor subtype, and family history.Semantic proximity Read ↗

Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2.Semantic proximity Read ↗

The risk of breast cancer in BRCA1 and BRCA2 mutation carriers without a first-degree relative with breast cancer.Semantic proximity Read ↗

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry.Semantic proximity Read ↗

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies.Semantic proximity Read ↗

Breast cancer risks in women with a family history of breast or ovarian cancer who have tested negative for a BRCA1 or BRCA2 mutation.Semantic proximity Read ↗

Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Increased rate of phenocopies in all age groups in BRCA1/BRCA2 mutation kindred, but increased prospective breast cancer risk is confined to BRCA2 mutation carriers.Semantic proximity Read ↗

Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

BRCA1/2 and clinical outcome in a monoinstitutional cohort of women with hereditary breast cancer.Semantic proximity Read ↗

Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.