Article
Prognosis of early-onset breast cancer based on BRCA1/2 mutation status in a French population-based cohort and review.
Breast cancer research and treatment - 1 Jan 2007
Bonadona Valérie, Dussart-Moser Sophie, Voirin Nicolas, Sinilnikova Olga M, Mignotte Hervé, Mathevet Patrice, Brémond Alain, Treilleux Isabelle, Martin Alain, Romestaing Pascale, Raudrant Daniel, Rudigoz René-Charles, Lenoir Gilbert M, Lasset Christine
Abstract excerpt
PURPOSE: The debate concerning poorer survival for patients with breast cancer (BC) carrying a BRCA1 germline mutation is unresolved, and requires additional data from population-based studies. PATIENTS AND METHODS: We followed 232 women with invasive BC under age 46, ascertained prospectively through a French population-based BC registry and tested for BRCA1/2 mutations (median follow-up: 82 months). We compared...
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