Article
The -174 G/C polymorphism of the interleukin-6 gene promoter and essential hypertension in an elderly Italian population.
Journal of human hypertension - 1 Sept 2002
Pola R, Flex A, Gaetani E, Pola P, Bernabei R
Abstract excerpt
Several studies have proposed a relationship between blood pressure and inflammation. Interleukin-6 (IL-6) is a multifunctional cytokine involved in inflammation and tissue injury and potentially influencing blood pressure. Recently, a common polymorphism of the IL-6 gene, associated with differences in the transcription rate of the protein, has been described. The aim of this study was to investigate a possible...
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