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Allelic variants in the interleukin-6 gene and essential hypertension in Japanese women.

Genes and immunity - 1 Nov 1999

Nakajima T, Ota N, Yoshida H, Watanabe S, Suzuki T, Emi M

Abstract excerpt

Genes that can be implicated in hypertension in experimental animals are plausible candidates in the pathogenesis of human hypertension. A recent genome-wide search for quantitative-trait loci (QTL) in hypertensive rats revealed a strong correlation between the interleukin-6 (IL-6) locus on rat chromosome 4 and systolic, diastolic, and mean arterial pressure in this mammalian species. To investigate a possible...

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PMID: 11196657
DOI: 10.1038/sj.gene.6363642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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