Article
The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with peripheral artery occlusive disease.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Sept 2002
Flex A, Gaetani E, Pola R, Santoliquido A, Aloi F, Papaleo P, Dal Lago A, Pola E, Serricchio M, Tondi P, Pola P
Abstract excerpt
OBJECTIVE AND DESIGN: high plasma levels of Interleukin-6 (IL-6) are found in patients with atherosclerotic disorders. Recently, a common polymorphism of the IL-6 gene promoter, influencing the transcription rate of the gene, has been described and associated with atherosclerosis of carotid and coronary arteries. The objective of this study was to test whether IL-6 gene promoter polymorphism is associated with...
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