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Article

Interleukin-6 promoter polymorphisms and susceptibility to atrial fibrillation in elderly Han Chinese patients with essential hypertension.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Nov 2012

Li Jing, Song Jie, Jiang Min-Hui, Zheng Jin-Guo, Gao Shu-Ping, Zhu Jian-Hua, Pan Min

Abstract excerpt

There is an accumulating body of evidence indicating a strong association between inflammation and the pathogenesis of atrial fibrillation (AF). Interleukin-6 (IL-6) is a pleiotropic cytokine, functions as a mediator of inflammatory response, and has both proinflammatory and anti-inflammatory properties. The aim of the present study was to investigate the association of the -634C/G polymorphism of the IL-6 gene...

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Atrial Fibrillation
China
Cholesterol
Genetic Association Studies
Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

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Identifiers

PMID: 22924939
DOI: 10.1089/jir.2012.0033
PMCID: PMC3493041

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