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Article

The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected].

Neuroreport - 16 Sept 2002

Pola Roberto, Flex Andrea, Gaetani Eleonora, Lago Antonio Dal, Gerardino Laura, Pola Paolo, Bernabei Roberto

Abstract excerpt

Interleukin-6 (IL-6) is a multifunctional cytokine playing a crucial role in inflammation and tissue injury. A role for this molecule in neurodegeneration and Alzheimer's disease (AD) has been proposed. The aim of this study was to evaluate the association between a common polymorphism of the IL-6 gene promoter and AD in the Italian population. We found that the frequency of the GG genotype was significantly...

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Source

Identifiers

PMID: 12352619
DOI: 10.1097/00001756-200209160-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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