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Article

Genetic heterogeneity of the envelope 2 gene and eradication of hepatitis C virus after a second course of interferon-alpha.

Journal of medical virology - 1 Oct 2002

Boulestin Anne, Sandres-Sauné Karine, Payen Jean-Louis, Alric Laurent, Dubois Martine, Pasquier Christophe, Vinel Jean-Pierre, Pascal Jean-Pierre, Puel Jacqueline, Izopet Jacques

Abstract excerpt

The heterogeneity of the envelope 2 (E2) gene of the hepatitis C virus (HCV) was involved in the sensitivity of HCV to interferon-alpha (IFN-alpha). To assess the factors leading to virus eradication by IFN-alpha, patients whose first treatment by IFN-alpha failed and who had virus eradication after a second treatment were studied. These patients were paired with subjects in whom both treatments failed. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12210411
DOI: 10.1002/jmv.10192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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