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Article

Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3).

European journal of immunology - 1 Aug 2002

Workman Creg J, Rice Dennis S, Dugger Kari J, Kurschner Cornelia, Vignali Dario A A

Abstract excerpt

CD223 (LAG-3) is an activation-induced cell surface molecule, structurally similar to the T cell coreceptor CD4, that binds MHC class II molecules with high affinity. Little is known about the expression and function of murine CD223. Here, we show that mRNA expression is restricted to the thymic medulla, splenic red pulp and sparse cells in the adult brain cortex. In contrast, surprisingly high expression was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12209638
DOI: 10.1002/1521-4141(200208)32:8<2255::AID-IMMU2255>3.0.CO;2-A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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