Article
A third sublineage of avian T cells can be identified with a T cell receptor-3-specific antibody.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1990
Char D, Sanchez P, Chen C L, Bucy R P, Cooper M D
Abstract excerpt
Avian homologues of mammalian gamma delta and alpha beta TCR, termed TCR1 and TCR2, have been identified in the chicken with specific mAb. A third TCR, dubbed TCR3, has been identified on a subpopulation of T cells that lack the TCR1 or TCR2 epitopes. We have now produced a mAb that identifies this TCR3 molecule. The anti-TCR3 antibody immunoprecipitates a CD3-associated heterodimer with a relative Mr of 88,000,...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Differentiation, T-Lymphocyte
- Birds
- CD4 Antigens
- CD8 Antigens
- Chickens
- DNA
- Molecular Weight
- Phenotype
- Receptors, Antigen, T-Cell