Article
Genotypes of alcohol-metabolizing enzymes and the risk for alcoholic chronic pancreatitis in Japanese alcoholics.
Alcoholism, clinical and experimental research - 1 Dec 1996
Matsumoto M, Takahashi H, Maruyama K, Higuchi S, Matsushita S, Muramatsu T, Okuyama K, Yokoyama A, Nakano M, Ishii H
Abstract excerpt
Genetic predisposition to alcoholism and alcoholic liver disease has been reported. However, genetic susceptibility to alcoholic pancreatitis is still a matter of debate. To determine it, we examined genotype patterns of aldehyde dehydrogenase (ALDH2), alcohol dehydrogenase (ADH2 and ADH3), and c...
Topics
- Adult
- Aged
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Chronic Disease
- Cytochrome P-450 CYP2E1
- Ethanol
- Female
- Gene Frequency
- Genotype
- Humans
- Isoenzymes
- Japan
- Male
- Middle Aged
- Pancreas
- Pancreatitis, Alcoholic