Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ALDH2 genotype, alcohol intake, and liver-function biomarkers among Japanese male workers.

Human genetics - 1 Jun 2000

Takeshita T, Yang X, Morimoto K

Abstract excerpt

A highly prevalent, atypical genotype in low Km aldehyde dehydrogenase (ALDH2) may influence alcohol-induced liver injury because of higher production of acetaldehyde in the liver. In the present study, we examined relationships between the ALDH2 genotype, alcohol intake, and liver-function biomarkers among Japanese male workers. Study subjects were 385 male workers in a metal plant in Japan, who were free from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine Transaminase
Share to Alcohol Drinking
Share to Aldehyde Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Aspartate Aminotransferases

Share to gamma-Glutamyltransferase

Share to Linear Models

Share to Liver Function Tests

Source

Identifiers

PMID: 10942105
DOI: 10.1007/s004390000314

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ALDH2 genotype, alcohol intake, and liver-function biomarkers among Japanese male workers.PMID 10942105Read ↗

Effect of ALDH2 and CYP2E1 gene polymorphisms on drinking behavior and alcoholic liver disease in Japanese male workers.Semantic proximity Read ↗

Role of ALDH2 in Hepatic Disorders: Gene Polymorphism and Disease PathogenesisSemantic proximity Read ↗

Effects of alcohol intake and low Km aldehyde dehydrogenase on hepatic function in a high hepatitis C virus-prevalent Japanese island population.Semantic proximity Read ↗

ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers.Semantic proximity Read ↗

Associations between aldehyde dehydrogenase 2 (ALDH2) genetic polymorphisms, drinking status, and hypertension risk in Japanese adult male workers: a case-control study.Semantic proximity Read ↗

Mean corpuscular volume and the aldehyde dehydrogenase-2 genotype in male Japanese workers.Semantic proximity Read ↗

Biological markers of alcoholism with respect to genotypes of low-Km aldehyde dehydrogenase (ALDH2) in Japanese subjects.Semantic proximity Read ↗

Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics.Semantic proximity Read ↗

Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population.Semantic proximity Read ↗

Association of an aldehyde dehydrogenase 2 (ALDH2) gene polymorphism with hyper-low-density lipoprotein cholesterolemia in a Japanese population.Semantic proximity Read ↗

Aldehyde Dehydrogenase, Liver Disease and CancerSemantic proximity Read ↗

Epidemiologic study of the association of low-Km mitochondrial acetaldehyde dehydrogenase genotypes with blood pressure level and the prevalence of hypertension in a general population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.