Article
Roles of the genetic variation of alcohol-metabolizing enzymes on biomarkers in trauma patients with excessive alcohol intake at emergency department.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2008
Tseng Yang-Ming, Jin Yi-Ru, Chen Ing-Jun, Huang Fong-Dee, Wu Szu-Hsien, Ma Hsu, Chen Sheng-Yi, Tsai Li-Yu, Tsai Shih-Meng, Lee Jang-Hwa
Abstract excerpt
BACKGROUND: Alcohol abuse has been implicated as an important factor for accidents. We evaluated the roles of different genetic combinations of the ADH2 and ALDH2 genotypes on biomarkers in trauma patients with excessive alcohol intake at our emergency department. METHODS: Blood samples were obtained from 80 patients and 88 age-matched controls. The biomarkers, including AST, ALT, GGT, and MDA, were assayed. The...
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