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Article

B-cell signaling: protein kinase Cdelta puts the brakes on.

Current biology : CB - 20 Aug 2002

Mathis Diane, King George L

Abstract excerpt

The phenotype of mice lacking the delta isoform of protein kinase C reveals that this isoform curtails signaling events after engagement of the antigen-specific receptor on B cells. The result is a state of non-responsiveness, termed anergy, that represents one form of immunological self-tolerance.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12194836
DOI: 10.1016/s0960-9822(02)01052-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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