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Article

Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p is required for efficient induction and execution of meiotic development.

Eukaryotic cell - 1 Feb 2002

Cooper Katrina F, Strich Randy

Abstract excerpt

The yeast C-type cyclin Ume3p/Srb11p and its cyclin-dependent kinase partner Ume5p/Srb10p repress the transcription of several genes required for meiotic recombination or meiosis I nuclear division. To relieve this repression, Srbllp is destroyed early in meiosis, prior to the first meiotic division. This report identifies two roles for Srb11p in regulating meiotic development. First, SRB11 is required for the...

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Identifiers

PMID: 12455972
DOI: 10.1128/EC.01.1.66-74.2002
PMCID: PMC118056

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