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Article

Loss of meiotic rereplication block in Saccharomyces cerevisiae cells defective in Cdc28p regulation.

Eukaryotic cell - 1 Jan 2005

Rice Lyndi M, Plakas Constantine, Nickels Joseph T

Abstract excerpt

Cdc28p is the major cyclin-dependent kinase in Saccharomyces cerevisiae. Its activity is required for blocking the reinitiation of DNA replication during mitosis. Here, we show that under conditions where Cdc28p activity is improperly regulated--either through the loss of function of the Schizosaccharomyces pombe wee1 ortholog Swe1p or through the expression of a dominant CDC28 allele, CDC28AF--diploid yeast...

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Source

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Identifiers

PMID: 15643060
DOI: 10.1128/EC.4.1.55-62.2005
PMCID: PMC544154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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